Laboratory for Structural Biology of G-protein Coupled Receptors

Head of the laboratory: Prof. Vadim Cherezov
Laboratory for Structural Biology of G-protein Coupled Receptors

About Lab

Activity in the Laboratory of Structural Biology of G-protein Coupled Receptors is focused on structural and functional research of G-protein Coupled Receptors (GPCR). We apply a multi-disciplinary, structural biological approach in which we combine computational methods with numerous biophysical techniques (crystallography, fluorescence of single molecules, electron microscopy, NMR, mass spectrometry, etc.) in order to find an answer to questions concerning the mechanisms of ligand recognition and signal transfer in GPCR. This project conducts a focused and comprehensive structure-function research on highly important but previously untackled targets from the GPCR superfamily. The results of these studies will provide scientists with essential information for designing new generation drugs with higher efficacy and minimal side effects.

Main Lab Members

Prof. Vadim Cherezov

Prof. Vadim Cherezov

Head of the laboratory

Dr. Alexey Mishin

Dr. Alexey Mishin

Deputy head

Dr. Petr Popov

Dr. Petr Popov

Computational group leader

Alexandra Luginina

Alexandra Luginina

Researcher

Polina Khorn

Polina Khorn

Researcher

Dr. Mikhail Shevtsov

Dr. Mikhail Shevtsov

Senior researcher

Anastasia Gusach

Anastasia Gusach

PhD student

Elizaveta Lyapina

Elizaveta Lyapina

PhD student

Nadezda Safronova

Nadezda Safronova

PhD student

Georgiy Khusainov

Georgiy Khusainov

PhD student


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